Chiral Separation Techniques.pdf

Chiral Separation Techniques PDF

Thoroughly revised, with either entirely new or completely updated contents, this is a practical manual for the small and large-scale preparation of enantiomerically pure products. The result is a vital resource for meeting the highest purity standards in the manufacture of chiral pharmaceuticals, food additives and related compounds. All the approaches covered here are highly relevant to modern manufacturing and quality control schemes in the pharmaceutical and biotech industries, addressing the increasingly important issue of drug safety in view of tougher regulatory standards worldwide.

Chiral Chromatography Thomas E. Beesley Advanced Separation Technologies Inc., Whippany, New Jersey, USA Raymond P. W. Scott Chemistry Department, Georgetown University, Washington DC, USA and Chemistry Department, Birkbeck College, University of London, UK Analytical techniques based on separation processes, such as chromatography and electrophoresis, are finding a growing range of

9783527611720 ISBN
Englisch SPRACHE
Chiral Separation Techniques.pdf


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Modern Methods for the Separation of Enantiomers - from Kilos to Tons - - Over 80% of drug candidates contain at least one chiral center - Increasingly complex molecules, requiring more advanced production methodologies -Three General Strategies -Chiral Pool -Asymmetric Synthesis -Resolution Chirality in Drug Pipeline •Is there an optimal approach to problem? •No – each stage is driven Chiral Separations | Annual Review of Analytical …

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