DNA-Ligand Interactions.pdf

DNA-Ligand Interactions PDF

This volume contains the texts of the nineteen lectures presented at the NATO-ASI - FEBS Course on DNA - ligand interactions: from drugs to proteins. The Advanced Study Institute (ASIl was held from August 30th to September 11th. 1986 in the Abbey of Fontevraud (France). The ASI was attended by 112 participants from a wide scientific horizon and from twentyone different countries. It was in some way a follow-up of the ASI held in Maratea. Italy in May 1981 and which was published in the NATO ASI Life Science series as volume 45. While much has been learned about the way the cellular machinery maintains and transmits the genetic heritage. as well as how these processes are regulated. little is Known about how the interactions between the various partners involved are taKing place. The interactions of drugs and proteins with nucleic acids are of evident importance in the understanding of these problems. The spectacular advances in recombinant DNA technology and the increased sophistication of biophysical techniques. in particular >:-ray diffraction and nuclear magnetic resonance. have created a scientific environment which is highly promising for the future of research in molecular biology. These advances permH the serious hope that biology on the molecular level may become a r-eality. Some of the contributions at the ASI presented the most recent advances in this e>:citing field.

This volume contains the texts of the nineteen lectures presented at the NATO- ASI - FEBS Course on "DNA - ligand interactions: from drugs to proteins.

1468453858 ISBN
Englisch SPRACHE
DNA-Ligand Interactions.pdf


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Sofia Voigt

DNA–ligand interactions gained and lost: light … A supramolecular five-component cascade is presented that enables light-controlled transport of an in situ modified ligand between three host systems based on the different complexation preferences of cyclodextrin, cucurbituril, and double-stranded DNA. The results point out novel approaches for the control of drug–DNA interactions in DNA-targeting therapy.

Matteo Müller

1 A new Monte Carlo based technique to study DNA-ligand interactions Israel Cabeza de Vaca1, Fátima Lucas1,2 and Victor Guallar1,3,* 1 Joint BSC-CRG-IRB Research Program in Computational Biology, Barcelona Supercomputing Center, c/Jordi Girona 29, 08034 Barcelona, Spain. 2 Anaxomics Biotech, Balmes 89, 08008 Barcelona, Spain 3 Institució Catalana de Recerca I Estudis Avançats, Passeig

Noel Schulze

28 Jan 2009 ... DNA-ligand interactions; protein-DNA interactions; protein-RNA interactions; protein-ligand interactions; binding kinetics. Literature & Tutorials:.

Jason Lehmann

Bonvin Lab

Jessica Kohmann

LABEL-FREE MONITORING OF DNA–LIGAND INTERACTIONS 95 In recent years, a range of techniques for the label-free and real time monitoring of biochemical interac-tions by using solid phases have found increasing at-tention. These methods allow monitoring of binding events at solid–liquid interfaces and therefore access