Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles.pdf

Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles PDF

In the past decade a most interesting story of the role played by the small nuclear RNPs, catalysts in RNA processing, has unfolded. Early investigations of the structure of these particles gave rise to hypotheses of their functions. As described in this book, these have been confirmed or are being tested by biochemical ex­ perimentation and most recently by the powerful technique of genetic analysis. Both biochemical and genetical approaches will also determine to what degree, and how, snRNPs and their cofactors participate in the differential expression of genes. As the details emerge and the number of snRNP species increases way beyond the six initially identified, one feels at the threshold of even greater things to come. The book covers many results in one of the most rapidly expanding fields of molecular biology. For this reason alone the specialist may detect some omissions and shortcomings. I hope they will be few. Instead of presenting a collation of conference reports with much overlap between them, this book has been written specially for the purpose of surveying the literature up to early 1987 in the snRNP field in a coherent manner, each of the seven chapters having been produced by connoisseurs of their field. While not each and every snRNP story can be covered in such a book, I hope that it will provide enjoyable and stimulating reading.

Here, we review the role of U1 snRNP in 3′ end mRNA processing, outline the ... and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles, ... shifted base-pairing to U1 snRNA,” Nature Structural and Molecular Biology, vol.

3.67 MB DATEIGRÖSSE
3642730221 ISBN
Englisch SPRACHE
Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles.pdf

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Sofia Voigt

The results indicate that nuclear targeting of U1 snRNA requires both a trimethylguanosine cap structure and binding of at least one common U snRNP protein. Using synthetic U6 snRNAs, it is further demonstrated that the trimethylguanosine cap structure can act in nuclear targeting in the absence of the common U snRNP proteins.

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Matteo Müller

Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles: Amazon.es: Max L. Birnstiel: Libros en idiomas extranjeros. Saltar al contenido principal . Prueba Prime Todos los departamentos. Ir Buscar Hola, Identifícate Cuenta y listas Identifícate

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Noel Schulze

Structure and function of major and minor small … OSTI.GOV Book: Structure and function of major and minor small nuclear ribonucleoprotein particles

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Jason Lehmann

Buy Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles Softcover reprint of the original 1st ed. 1988 by Max L. Birnstiel (ISBN: 9783642730221) from Amazon's Book Store. Everyday low prices and free delivery on eligible orders. Small nuclear ribonucleoprotein polypeptide E - …

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Jessica Kohmann

The first cleavage in mammalian pre-rRNA maturation occurs near the 5′ end within the 5′ external transcribed spacer. Using mouse cell extracts, we show that this processing is abolished by micrococcal nuclease pretreatment. Autoantibodies that recognize the U3, U8, and U13 snRNPs (anti-fibrillarin) deplete processing activity from the extract and selectively immunoprecipitate … Saccharomyces cerevisiae telomerase is an Sm …