Prognostic Impact of Apoptosis Markers (Fas & FasL) in Bladder Cancer.pdf

Prognostic Impact of Apoptosis Markers (Fas & FasL) in Bladder Cancer PDF

Hazem Elmansy

Bladder cancer is a global health issue. In the endemic areas of Egypt, schistosomiasis is a leading cause of bladder cancer. Prognostic indicators are required to further identify which tumor should be treated aggressively early on, in order to improve surveillance. The Fas-Fas Ligand (Fas-FasL) system has been recognized as a major pathway for the induction of apoptosis in cells and tissues. Fas-mediated apoptosis is deeply involved in cancer cell death, brought about by the immune system. The interaction of Fas and Fas Ligand contributes to cytotoxic T-lymphocyte and natural killer-cell mediated cytotoxicity against cancer cells. This study was performed to assess the importance of the apoptosis markers (Fas and FasL) in bilharzial versus non-bilharzial bladder cancer, in order to detect the possible diagnostic &/or prognostic potentials of this factor.

1 Sep 2019 ... Mechanistically, the luciferase report assay-identified FAS ligand ... apoptosis of gastric cancer cells through regulation of Fas/FasL. ... Moreover, LRRN1 may be a potential prognostic biomarker and therapeutic target for GC. ... Purple sweet potato anthocyanin exerts antitumor effect in bladder cancer. 13 Jan 2015 ... Changes in the apoptosis receptor Fas/FasL also enable evasion of the ... Aberrant expression of microRNA in bladder cancer cells was first reported in 2007 (12). ... The major consequences of immune evasion of tumor cells are invasive ... protein in urinary bladder cancer: a marker of favorable prognosis.

6.58 MB DATEIGRÖSSE
3659342777 ISBN
Englisch SPRACHE
Prognostic Impact of Apoptosis Markers (Fas & FasL) in Bladder Cancer.pdf

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